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Brief Report:Fulminating Fat Embolism Syndrome Caused by Paradoxical Embolism Through a Patent Foramen Ovale NEJM 329:926-929, 9611993., Pell,A.C.H.,et al, 1993 See this aricle in Pubmed Article Abstract The post-traumatic fat embolism syndrome is a multisystem disorder characterized by pulmonary and neurologic dysfunction,pyrexia,and a petechial rash.More than a century after the first descriptions of the fat embolism syndrome,the cause of fat emboli and the pathogenesis of the systemic manifestations of this disorder remain incompletely understood.We describe a patient undergoing treatment of a femoral fracture in whom massive fat embolism was demonstrated by transesophageal echocardiography. Acute cor pulmonale developed,precipitating paradoxical fat embolism across a patent foramen ovale,with the subsequent development of the fat embolism syndrome.Embolism of fat across a patent foramen ovale is a possible mechanism responsible for the systemic features of fat embolism syndrome.

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(click to filter results - removes previous filter) echocardiogram echocardiogram,transesophageal embolism embolism,fat embolism,paradoxical fracture,long bone patent foramen ovale trauma

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